Biostimulator for an extra boost of vibrancy to the skin


Frau mit Falten an den Augen symbolisiert Karisma-Filler

Changes in the skin such as wrinkles and lines are a major disruptive factor for many people, as they make affected people look older and less ‘vital’. Although there are different ways to correct these changes, more and more people are looking for natural and safe options. Dr Duve applies the innovative Karisma biostimulator as a solution. As a bio-filling soft filler, Karisma offers a safe and effective way to correct age-related wrinkles and sagging skin on the face and restore a natural as well as youthful appearance.

Learn more about this innovative treatment.



EUR 450


Approx. 30 minutes


No or local anaesthetic upon request



Advantages of a Karisma treatment

  • Biological ingredients
  • Very good tolerance
  • Long-lasting, natural results

Treatment areas for Karisma fillers

Face, neck, décolleté

What is Karisma filler and how does it work?

Karisma is a bio-filling soft filler used in aesthetic medicine to correct age-related changes in the face. Unlike traditional fillers, Karisma is made from natural ingredients – including hyaluronic acid, carboxymethyl cellulose and type I collagen – making it a safe option for facial wrinkle treatment.

It is a safe and effective alternative to traditional fillers. The filler stimulates the body’s natural production of collagen and hyaluronic acid – for a more youthful appearance.

Frau mit einer Faltenbehandlung durch Karisma-Filler

For whom is the treatment suitable?

Overall, Karisma offers a safe and effective way to correct age-related changes in the face and thus achieve a natural and youthful appearance. Therefore, the filler is a recommended option for anyone who wants to offset volume loss and sagging skin. Small, superficial scars can also be reduced. However, it is important that the treatment is carried out by an experienced doctor such as Dr Duve.

What should be considered before the treatment?

Before the treatment, a thorough preliminary examination is carried out to ensure that the Karisma filler is suitable for you as a patient. At this time, Dr Duve will also discuss your medical history with you as well as any allergies you may have. If possible, refrain from taking blood thinners such as aspirin a few days beforehand, and do not wear make-up in the treatment area on the day of the treatment.

What is the procedure for the Karisma filler treatment?

The application begins with a thorough cleansing and disinfection of the area to be treated. The filler is then injected under the skin with a very fine needle to fill deep wrinkles and lines and tighten the skin. The treatment is painless, but if the patient wishes, an anaesthetic ointment can be applied beforehand. With preparation and follow-up, the procedure takes about 30 minutes.

What should I consider after the treatment?

There is no downtime after the treatment, meaning you can return to work immediately. However, in order to achieve the best possible result and avoid potential complications, a few aftercare measures are recommended. This includes cooling the treated area to reduce swelling and pain. Apart from that, protect the treated area from direct sunlight to avoid discolouration or irritation. Do not exercise on the treatment day and refrain from heavy lifting.

When will the result be visible?

Immediately after the treatment with Karisma, you can already expect a first improvement. Further results will appear over the course of the next few weeks. Wrinkles and lines are softened, and the tissue gains new volume. More importantly, the result is natural and lasts for up to a year.

What are the risks?

Karisma consists of hyaluronic acid-based ingredients that are already present in the skin. Therefore, the risk of allergic reactions or intolerances is low. Moreover, Karisma is applied under careful medical supervision by Dr Stefan Duve, MD, allowing for safe treatment performed under the highest hygiene standards. Slight swelling or redness may occur after application, but it will disappear after a few days.

Frequently asked questions about the Karisma filler

Answers from the expert Dr Duve

Is the Karisma filler treatment painful?

Treatment with the Karisma filler is painless. Depending on the patient’s sensitivity, a local anaesthetic may be used to make the application more comfortable. –

How long does the result of the Karisma filler treatment last?

Depending on the individual needs and age of the patient, the result of Karisma filler treatment usually lasts up to 12 months. Repeat treatment may be required to maintain the desired result. –

Can the Karisma filler be used on any type of wrinkle?

The Karisma filler is best suited for fine lines and wrinkles on the face, especially around the eyes, forehead and mouth. While larger wrinkles or deeper furrows can also be treated, more treatments may be required to achieve the desired result. –

Personal consultation


Doctor Duve mit seiner Pflegelinie

Schedule an appointment for a personal consultation now by phone or via our contact form. You are also welcome to use our online consultation for your first meeting.




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